Bureau de la recherche
Le service de neurochirurgie de La Pitié-Salpêtrière abrite une équipe dédiée à l’organisation et à la réalisation de la recherche au sein du service sur les versants fondamental, translationnel et industriel, permettant une interaction riche et fructueuse entre le service de soins et les partenaires académiques et industriels.
Nos publication scientifiques
GAB1 overexpression identifies hedgehog-activated anterior skull base meningiomas Boetto J, Lerond J, Peyre M, Tran S, Marijon P, Kalamarides M, Bielle F Neuropathol Appl Neurobiol. 2021 May 31 Consulter la publication |
Targeting the CSF1/CSF1R Axis is a Potential Treatment Strategy for Malignant Meningiomas Yeung J, Yaghoobi V, Miyagishima D, Vesely MD, Zhang T, Badri T, Nassar A, Han X, Sanmamed MF, Youngblood M, Peyre M, Kalamarides M, Rimm DL, Gunel M, Chen L Neuro Oncol. 2021 Apr 29 Consulter la publication |
Meningiomas from a developmental perspective: exploring the crossroads between meningeal embryology and tumorigenesis Boetto J, Peyre M, Kalamarides M. Acta Neurochir (Wien) 2021 Jan;163(1):57-66 Consulter la publication |
Associations of meningioma molecular subgroup and tumor recurrence Youngblood MW, Miyagishima DF, Jin L, Gupte T, Li C, Duran D, Montejo JD, Zhao A, Sheth A, Tyrtova E, Özduman K, Iacoangeli F, Peyre M, Boetto J, Pease M, Avşar T, Huttner A, Bilguvar K, Kilic T, Pamir MN, Amankulor N, Kalamarides M, Erson-Omay EZ, Günel M, Moliterno J Neuro Oncol. 2021 May 5;23(5):783-794 Consulter la publication |
Prognostic Value of Histopathological Features and Loss of H3K27me3 Immunolabeling in Anaplastic Meningioma: A Multicenter Retrospective Study Gauchotte G, Peyre M, Pouget C, Cazals-Hatem D, Polivka M, Rech F, Varlet P, Loiseau H, Lacomme S, Mokhtari K, Kalamarides M, Bielle F J Neuropathol Exp Neurol. 2020 Jul 1;79(7):754-762 Consulter la publication |
Correlations between genomic subgroup and clinical features in a cohort of more than 3000 meningiomas Youngblood MW, Duran D, Montejo JD, Li C, Omay SB, Özduman K, Sheth AH, Zhao AY, Tyrtova E, Miyagishima DF, Fomchenko EI, Hong CS, Clark VE, Riche M, Peyre M, Boetto J, Sohrabi S, Koljaka S, Baranoski JF, Knight J, Zhu H, Pamir MN, Avşar T, Kilic T, Schramm J, Timmer M, Goldbrunner R, Gong Y, Bayri Y, Amankulor N, Hamilton RL, Bilguvar K, Tikhonova I, Tomak PR, Huttner A, Simon M, Krischek B, Kalamarides M, Erson-Omay EZ, Moliterno J, Günel M J Neurosurg. 2019 Oct 25:1-10 Consulter la publication |
Selective vulnerability of the primitive meningeal layer to prenatal Smo activation for skull base meningothelial meningioma formation Boetto J, Apra C, Bielle F, Peyre M, Kalamarides M Oncogene. 2018 Sep;37(36):4955-4963 Consulter la publication |
Pazopanib efficacy in recurrent central nervous system hemangiopericytomas Apra C, Alentorn A, Mokhtari K, Kalamarides M, Sanson M J Neurooncol. 2018 Sep;139(2):369-372 Consulter la publication |
De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors Peyre M, Gauchotte G, Giry M, Froehlich S, Pallud J, Graillon T, Bielle F, Cazals-Hatem D, Varlet P, Figarella-Branger D, Loiseau H, Kalamarides M Neuro Oncol. 2018 Jul 5;20(8):1113-1121 Consulter la publication |
Progestin-associated shift of meningioma mutational landscape Peyre M, Gaillard S, de Marcellus C, Giry M, Bielle F, Villa C, Boch AL, Loiseau H, Baussart B, Cazabat L, Raffin-Sanson ML, Sanson M, Kalamarides M Ann Oncol. 2018 Mar 1;29(3):681-686 Consulter la publication |
Diffuse midline skull base meningiomas: identification of a rare and aggressive subgroup of meningiomas Peyre M, Feuvret L, Sanson M, Navarro S, Boch AL, Loiseau H, Kalamarides M J Neurooncol. 2017 Jul;133(3):633-639 Consulter la publication |
SMO mutation status defines a distinct and frequent molecular subgroup in olfactory groove meningiomas Boetto J, Bielle F, Sanson M, Peyre M, Kalamarides M Neuro Oncol. 2017 Mar 1;19(3):345-351 Consulter la publication |
PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss Peyre M, Salaud C, Clermont-Taranchon E, Niwa-Kawakita M, Goutagny S, Mawrin C, Giovannini M, Kalamarides M Oncotarget. 2015 Oct 20;6(32):32713-22 Consulter la publication |
mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma Giovannini M, Bonne NX, Vitte J, Chareyre F, Tanaka K, Adams R, Fisher LM, Valeyrie-Allanore L, Wolkenstein P, Goutagny S, Kalamarides M Neuro Oncol. 2014 Apr;16(4):493-504 Consulter la publication |
High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression Goutagny S, Nault JC, Mallet M, Henin D, Rossi JZ, Kalamarides M Brain Pathol. 2014 Mar;24(2):184-9 Consulter la publication |
Miniaturized handheld confocal microscopy identifies focal brain invasion in a mouse model of aggressive meningioma Peyre M, Clermont-Taranchon E, Stemmer-Rachamimov A, Kalamarides M Brain Pathol. 2013 Jul;23(4):371-7 Consulter la publication |
Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation Peyre M, Stemmer-Rachamimov A, Clermont-Taranchon E, Quentin S, El-Taraya N, Walczak C, Volk A, Niwa-Kawakita M, Karboul N, Giovannini M, Kalamarides M Oncogene. 2013 Sep 5;32(36):4264-72 Consulter la publication |
Long-term follow-up of 287 meningiomas in neurofibromatosis type 2 patients: clinical, radiological, and molecular features Goutagny S, Bah AB, Henin D, Parfait B, Grayeli AB, Sterkers O, Kalamarides M Neuro Oncol. 2012 Aug;14(8):1090-6 Consulter la publication |
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes Kalamarides M, Stemmer-Rachamimov AO, Niwa-Kawakita M, Chareyre F, Taranchon E, Han ZY, Martinelli C, Lusis EA, Hegedus B, Gutmann DH, Giovannini M Oncogene. 2011 May 19;30(20):2333-44 Consulter la publication |
